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Probiotic Drops

One preparation, one daily dose, whatever you take it for.

$250per 30-day protocol · two 30 ml applicators · $199 on a one-year subscription · free DHL from three applicators

The stable metabolites of the 3-million-year-old Bacillus F organism, cold-processed into precise daily drops for cellular resilience and antioxidant defense.

Best for: NMN-experienced longevity buyers, biohackers tracking biomarkers, professionals 35–65.
  • Postbiotic, no live bacteria
  • 2 ml daily · two presses · sublingual
  • Two 30 ml applicators per 30-day protocol
  • Freezer unopened, fridge once open
  • Nothing to prepare
  • Patent WO2012060729
Bacillus F sublingual applicator pen tilted nozzle-down, a single drop falling toward dark still water with ripples. The longevity postbiotic supplement by Bacillus F OÜ, Tallinn, Estonia.
Key takeaways
  • Probiotic Drops: Liquid-drop delivery: precise, sublingual, travel-ready.
  • A postbiotic: the stable metabolites, not live bacteria. Same on day one as on day thirty.
  • Derived from the Bacillus F strain, patented as WO2012060729 with five national patents.
  • Liquid drops: 2 ml daily (two 1 ml presses), sublingual, two 30 ml applicators per 30-day protocol.
  • Sits alongside NMN and spermidine rather than replacing them. It works on oxidative-stress defense, a different mechanism.

About the formulation

People searching for probiotic drops usually want two things: a liquid format instead of capsules, and something to do with beneficial bacteria. We can give you the first without qualification. The second needs a correction, and it is a correction in your favour.

Bacillus F is a postbiotic, not a probiotic. The applicator holds what the organism produces, not the organism. If you specifically need live cultures, say because you are rebuilding gut flora after antibiotics, this is honestly not the product. A multi-strain probiotic is what you want, and we would rather tell you that than take the order.

If what you actually wanted was the benefit people associate with beneficial bacteria, minus the fragility of live products, the comparison below is worth your time.

How it works

A probiotic works through a chain of events. The organisms have to survive the bottle, survive stomach acid, reach the intestine alive, and then establish themselves against whatever is already living there. Every link loses some. That is why those products carry CFU counts that decline over shelf life and results that vary so much from person to person.

A postbiotic removes the chain. The metabolites are produced in a controlled fermentation, separated, and stabilised. Nothing needs to survive anything. The dose you take is the dose that arrives.

In practice that means no viability anxiety and no wondering whether this batch is as active as the last. Keep the unopened applicator in the freezer and the one in use in the fridge, and it stays what it was. For a habit meant to run for months, that kind of reliability is usually what decides whether the habit survives.

There is one situation where both formats make sense together. If you are rebuilding gut flora after a course of antibiotics, a live-culture product is doing a job this preparation can't, and nothing stops you running both: different mechanisms, different goals, no known interaction. We just want you to know which product is doing which job.

Specifications

FormatSublingual applicator pen, clear cartridge with measured-dose tip
Active fractionCell-free Bacillus F metabolite complex (postbiotic)
Daily dose2 ml (two 1 ml presses), sublingual, morning
Protocol length30 days per protocol (two applicators) · 90 days recommended before re-testing
StorageFreezer until opened, fridge once open
OriginFermented & bottled in the EU · strain from Yakutia permafrost
DocumentationPatent WO2012060729 · deposited genome sequence
Live organismsNone. Postbiotic metabolite fraction
Bacillus F sublingual applicator pen standing on a white laboratory bench beside a glass petri dish, with a microscope and a rack of test tubes softly out of focus behind it. longevity postbiotic supplement by Bacillus F OÜ, Tallinn, Estonia.
Two Bacillus F sublingual applicator pens standing upright in a refrigerator door shelf next to a bottle of milk and a jar of olives — the open-applicator storage the protocol asks for. longevity postbiotic supplement by Bacillus F OÜ, Tallinn, Estonia.

Compliance & standards

The strain and its applications are covered by international patent WO2012060729 plus five national patents, and the organism is sequenced and deposited, so every batch comes from the same defined organism. The patent scans and the comet-assay imaging are published openly on the Science page.

Marketed as a dietary supplement, not a medicine. Statements have not been evaluated by the FDA.

What to expect

Expect no gut-flora effect, because nothing in the applicator is alive to colonise anything. If a shift in gut flora is your goal, this is the wrong product and a multi-strain probiotic is the right one.

What you can expect is consistency: the same potency from the first press to the last, and no guessing about whether the product you paid for is still the product. For a habit meant to run for months, that is most of what matters.

Use cases

  • Capsule avoiders who want a measured liquid dose from a precision applicator.
  • People whose probiotic routine keeps breaking, because viability counts and expiry dates made it hard to trust.
  • Format comparison shoppers deciding between live-culture and postbiotic approaches on the merits.

Not sure where it fits? Start with Bacillus F vs NMN, our most-read comparison.

Available in your country
Postbiotic drops · United StatesPostbiotic drops · United KingdomPostbiotic drops · CanadaPostbiotic drops · JapanPostbiotic drops · GermanyPostbiotic drops · FrancePostbiotic drops · SpainPostbiotic drops · EU-wide

Frequently asked

Probiotics are live organisms that have to survive digestion and settle in the gut. A postbiotic skips that: you take the finished metabolites, so the dose is consistent and nothing has to stay alive. Same organism, far more predictable.

Yes. Bacillus F works on oxidative-stress defense, NMN on NAD+, spermidine on autophagy. Three separate mechanisms. Plenty of customers run all three; the comparison guides in Learn go through it.

How it feels varies from person to person, so judge it by numbers. Take a baseline biological-age or oxidative-stress panel, run 90 days, re-test. The protocol is built around that rhythm.

The fermentation runs are small and every batch has to pass before it is released. Monthly capacity is capped, so we confirm availability for your country before charging anything.

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Support
Immune & Energy Support
Daily immune resilience and steady energy. The same drops, taken for defense.
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Limited monthly batches. We confirm availability for your country within 48 hours.

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