Key takeaways
- DNA Repair Supplement: Formulated around DNA-integrity markers.
- A postbiotic: the stable metabolites, not live bacteria. Same on day one as on day thirty.
- Derived from the Bacillus F strain, patented as WO2012060729 with five national patents.
- Liquid drops: 2 ml daily (two 1 ml presses), sublingual, two 30 ml applicators per 30-day protocol.
- Sits alongside NMN and spermidine rather than replacing them. It works on oxidative-stress defense, a different mechanism.
About the formulation
The most technical page in the set, and the one where wording matters most. This product is built around DNA-integrity markers, meaning integrity is what we measure and image. That is a statement about method. It is not a claim that the preparation repairs anyone's DNA.
The difference matters. Cells have sophisticated repair machinery of their own, and no supplement stands in for it. What can be observed in a lab is whether cells hit with an oxidative stressor show more or less DNA fragmentation depending on what they were treated with beforehand. That is an observation about damage, imaged directly.
If you came here expecting something that rewrites damaged sequence, we would rather fix the expectation than sell into it.
How it works
The method is again the comet assay. What makes it useful is that it works at single-cell resolution. Instead of averaging a population it shows the spread: how many cells are intact, how many are badly fragmented, and how wide the distribution is.
In the reference experiments, cells challenged with an oxidative stressor showed shorter comet tails when pre-treated with the Bacillus F postbiotic than when not. A short tail means DNA that didn't migrate, which means DNA that stayed mostly in one piece.
This is in vitro work and we label it that way wherever it appears. It is not a human trial. We don't claim one exists, and anyone in this category claiming clinical DNA-repair outcomes without a registration number and published results deserves your suspicion.
If you'd rather evaluate the method than take our word for it: the comet assay has been in routine use for genotoxicity testing since the 1980s and is well described in the open literature. We publish our own imaging rather than only citing other people's, and we say "in vitro" every time. Publish the images, state the limits. That is all we are claiming here.
Specifications
| Format | Sublingual applicator pen, clear cartridge with measured-dose tip |
| Active fraction | Cell-free Bacillus F metabolite complex (postbiotic) |
| Daily dose | 2 ml (two 1 ml presses), sublingual, morning |
| Protocol length | 30 days per protocol (two applicators) · 90 days recommended before re-testing |
| Storage | Freezer until opened, fridge once open |
| Origin | Fermented & bottled in the EU · strain from Yakutia permafrost |
| Documentation | Patent WO2012060729 · deposited genome sequence |
| Evidence type | In vitro comet-assay imaging, not a human clinical trial |
Compliance & standards
The strain and its applications are covered by international patent WO2012060729 plus five national patents, and the organism is sequenced and deposited, so every batch comes from the same defined organism. The patent scans and the comet-assay imaging are published openly on the Science page.
Marketed as a dietary supplement, not a medicine. Statements have not been evaluated by the FDA.
What to expect
Expect careful wording on this page, because the subject invites sloppy wording everywhere else. We are describing an imaging method and what it showed in vitro, not an outcome in your body.
No consumer test will tell you your DNA damage burden changed because of a supplement. If you want the closest thing, find a lab that offers an oxidative-DNA marker, take two baselines so you know your noise floor, and change one thing.
Use cases
- The mechanism-first reader who wants to understand the assay before considering the product.
- Quantified-self users tracking DNA-damage or oxidative markers in a structured panel.
- Practitioners who need to see the method before recommending anything.
Not sure where it fits? Start with Bacillus F vs NMN, our most-read comparison.
Frequently asked
Related solutions
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